JPH03875B2 - - Google Patents

Info

Publication number
JPH03875B2
JPH03875B2 JP57193436A JP19343682A JPH03875B2 JP H03875 B2 JPH03875 B2 JP H03875B2 JP 57193436 A JP57193436 A JP 57193436A JP 19343682 A JP19343682 A JP 19343682A JP H03875 B2 JPH03875 B2 JP H03875B2
Authority
JP
Japan
Prior art keywords
group
demethoxy
amino
demethoxyistamycin
tri
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57193436A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5984899A (ja
Inventor
Hamao Umezawa
Shinichi Kondo
Daishiro Ikeda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP57193436A priority Critical patent/JPS5984899A/ja
Priority to US06/545,686 priority patent/US4479943A/en
Priority to DE8383306537T priority patent/DE3372775D1/de
Priority to EP83306537A priority patent/EP0108563B1/en
Publication of JPS5984899A publication Critical patent/JPS5984899A/ja
Publication of JPH03875B2 publication Critical patent/JPH03875B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP57193436A 1982-11-05 1982-11-05 ３−デメトキシイスタマイシンｂ誘導体 Granted JPS5984899A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP57193436A JPS5984899A (ja) 1982-11-05 1982-11-05 ３−デメトキシイスタマイシンｂ誘導体
US06/545,686 US4479943A (en) 1982-11-05 1983-10-26 3-Demethoxyistamycin B, the 2"-N-formimidoyl derivative thereof and pharmaceutical composition containing same
DE8383306537T DE3372775D1 (en) 1982-11-05 1983-10-27 3-demethoxyistamycin b and its 2"-n-formimidoyl derivative
EP83306537A EP0108563B1 (en) 1982-11-05 1983-10-27 3-demethoxyistamycin b and its 2"-n-formimidoyl derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57193436A JPS5984899A (ja) 1982-11-05 1982-11-05 ３−デメトキシイスタマイシンｂ誘導体

Publications (2)

Publication Number Publication Date
JPS5984899A JPS5984899A (ja) 1984-05-16
JPH03875B2 true JPH03875B2 (en]) 1991-01-09

Family

ID=16307949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57193436A Granted JPS5984899A (ja) 1982-11-05 1982-11-05 ３−デメトキシイスタマイシンｂ誘導体

Country Status (4)

Country Link
US (1) US4479943A (en])
EP (1) EP0108563B1 (en])
JP (1) JPS5984899A (en])
DE (1) DE3372775D1 (en])

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59216898A (ja) * 1983-05-25 1984-12-06 Microbial Chem Res Found ３−デメトキシイスタマイシンｂの低毒性誘導体
JPS6042394A (ja) * 1983-08-18 1985-03-06 Kowa Co 新規なアミノグリコシド及びその製法
US4567165A (en) * 1984-05-08 1986-01-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai N-Methanesulfonic acid derivatives of 3-demethoxyistamycin B

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
JPS577493A (en) * 1980-06-17 1982-01-14 Kowa Co Novel aminoglycoside
DE3160643D1 (en) * 1980-05-22 1983-08-25 Kowa Co Novel aminoglycosides, and antibiotic use thereof
JPS56164197A (en) * 1980-05-22 1981-12-17 Kowa Co Novel aminoglycoside
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
JPS5750996A (en) * 1980-09-11 1982-03-25 Microbial Chem Res Found 3-o-demthylistamycin b derivative

Also Published As

Publication number Publication date
US4479943A (en) 1984-10-30
JPS5984899A (ja) 1984-05-16
DE3372775D1 (en) 1987-09-03
EP0108563B1 (en) 1987-07-29
EP0108563A1 (en) 1984-05-16

Similar Documents

Publication Publication Date Title
US4170642A (en) Derivatives of kanamycin A
US6140479A (en) Erythromycin a derivatives
JPH03875B2 (en])
KR920003838B1 (ko) I-N-(ω-아미노-α-히드록시알카노일)-2', 3'-디데옥시가나마이신 A의 제조방법
IE47271B1 (en) Process for the preparation of 1-n-acyl-aminoglycosides
CA1175818A (en) Derivatives of istamycins a and b and their preparation
JPS632271B2 (en])
CA1088080A (en) Fortimicin derivatives and method for production thereof
HK51584A (en) Process for the preparation of 1-n-acyl-aminoglycosides
JPH0764866B2 (ja) １−ｎ−（４−アミノ−３−フルオロ−２−ヒドロキシブチリル）カナマイシン類
JPS631954B2 (en])
JPH0130837B2 (en])
EP0094625B1 (en) Novel aminoglycosides and process for production thereof
JPS633874B2 (en])
EP0185323B1 (en) 2',3'-dideoxy-2'-fluorokanamycin a and 1-n-(alpha-hydroxy-omega-aminoalkanoyl) derivatives thereof
JPH0134231B2 (en])
JP3215732B2 (ja) 耐性菌に有効なジベカシン誘導体またはアルベカシン誘導体とそれらの製造法
JPS6362514B2 (en])
JPS6312079B2 (en])
EP0236942B1 (en) 2'-deamino-2'-hydroxyistamycin bo derivatives of low toxicity
JPS632268B2 (en])
JPS6362513B2 (en])
JPH0134230B2 (en])
JPH0367076B2 (en])
JPS631949B2 (en])